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Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds
BACKGROUND: Midkine is a heparin-binding cytokine and is involved in etiology of various diseases. Thus, midkine inhibitors are expected to be helpful in treatment of many diseases. METHODS: We developed a simple assay for midkine activity based on midkine-dependent migration of osteblastic cells. M...
Autores principales: | Matsui, Takashi, Ichihara-Tanaka, Keiko, Lan, Chen, Muramatsu, Hisako, Kondou, Toshiharu, Hirose, Chizuru, Sakuma, Sadatoshi, Muramatsu, Takashi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898662/ https://www.ncbi.nlm.nih.gov/pubmed/20565917 http://dx.doi.org/10.1186/1755-7682-3-12 |
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