The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells

BACKGROUND: Regulator of chromosome condensation 1 (RCC1) is the guanine nucleotide exchange factor for Ran GTPase. Localised generation of Ran-GTP by RCC1 on chromatin is critical for nucleocytoplasmic transport, mitotic spindle assembly and nuclear envelope formation. Both the N-terminal tail of R...

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Detalles Bibliográficos
Autores principales: Hitakomate, Ekarat, Hood, Fiona E, Sanderson, Helen S, Clarke, Paul R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898669/
https://www.ncbi.nlm.nih.gov/pubmed/20565941
http://dx.doi.org/10.1186/1471-2121-11-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898669/
https://www.ncbi.nlm.nih.gov/pubmed/20565941
http://dx.doi.org/10.1186/1471-2121-11-43

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