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A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention
BACKGROUND: Centrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation of cyclin/cyclin-dependent kinase 2 (CDK2) activity has previously been shown to be critically involved in centrosom...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898706/ https://www.ncbi.nlm.nih.gov/pubmed/20565777 http://dx.doi.org/10.1186/1476-4598-9-153 |