Co-lethality studied as an asset against viral drug escape: the HIV protease case

BACKGROUND: Co-lethality, or synthetic lethality is the documented genetic situation where two, separately non-lethal mutations, become lethal when combined in one genome. Each mutation is called a "synthetic lethal" (SL) or a co-lethal. Like invariant positions, SL sets (SL linked couples...

Descripción completa

Detalles Bibliográficos
Autores principales: Brouillet, Sophie, Valere, Thomas, Ollivier, Emmanuelle, Marsan, Laurent, Vanet, Anne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898770/
https://www.ncbi.nlm.nih.gov/pubmed/20565756
http://dx.doi.org/10.1186/1745-6150-5-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898770/
https://www.ncbi.nlm.nih.gov/pubmed/20565756
http://dx.doi.org/10.1186/1745-6150-5-40

Ejemplares similares