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Co-lethality studied as an asset against viral drug escape: the HIV protease case
BACKGROUND: Co-lethality, or synthetic lethality is the documented genetic situation where two, separately non-lethal mutations, become lethal when combined in one genome. Each mutation is called a "synthetic lethal" (SL) or a co-lethal. Like invariant positions, SL sets (SL linked couples...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898770/ https://www.ncbi.nlm.nih.gov/pubmed/20565756 http://dx.doi.org/10.1186/1745-6150-5-40 |