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Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-β1 in normal human lung fibroblasts (NHLF)

BACKGROUND: Airway remodelling is thought to be under the control of a complex group of molecules belonging to the Transforming Growth Factor (TGF)-superfamily. The Bone Morphogenetic Proteins (BMPs) belong to this family and have been shown to regulate fibrosis in kidney and liver diseases. However...

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Detalles Bibliográficos
Autores principales: Pegorier, Sophie, Campbell, Gaynor A, Kay, A Barry, Lloyd, Clare M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898775/
https://www.ncbi.nlm.nih.gov/pubmed/20573231
http://dx.doi.org/10.1186/1465-9921-11-85