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Anti-Cancer Effect of HIV-1 Viral Protein R on Doxorubicin Resistant Neuroblastoma

Several unique biological features of HIV-1 Vpr make it a potentially powerful agent for anti-cancer therapy. First, Vpr inhibits cell proliferation by induction of cell cycle G2 arrest. Second, it induces apoptosis through multiple mechanisms, which could be significant as it may be able to overcom...

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Detalles Bibliográficos
Autores principales: Zhao, Richard Y., Liang, Dong, Li, Ge, Larrimore, Christopher W., Mirkin, Bernard L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898807/
https://www.ncbi.nlm.nih.gov/pubmed/20628645
http://dx.doi.org/10.1371/journal.pone.0011466