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miR-17–92 cluster: ups and downs in cancer and aging

The miR-17–92 cluster encoding 6 single mature miRNAs was identified a couple of years ago to contain the first oncogenic miRNAs. Now, one of these 6 miRNAs, miR-19 has been identified as the key responsible for this oncogenic activity. This in turn reduces PTEN levels and in consequence activates t...

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Detalles Bibliográficos
Autores principales: Grillari, Johannes, Hackl, Matthias, Grillari-Voglauer, Regina
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899009/
https://www.ncbi.nlm.nih.gov/pubmed/20437201
http://dx.doi.org/10.1007/s10522-010-9272-9