Metabolic assessment of a novel chronic myelogenous leukemic cell line and an imatinib resistant subline by (1)H NMR spectroscopy

The goal of this study was to examine metabolic differences between a novel chronic myelogenous leukemic (CML) cell line, MyL, and a sub-clone, MyL-R, which displays enhanced resistance to the targeted Bcr-Abl tyrosine kinase inhibitor imatinib. (1)H nuclear magnetic resonance (NMR) spectroscopy was...

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Detalles Bibliográficos
Autores principales: Dewar, Brian J., Keshari, Kayvan, Jeffries, Rex, Dzeja, Petras, Graves, Lee M., Macdonald, Jeffrey M.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899017/
https://www.ncbi.nlm.nih.gov/pubmed/20676217
http://dx.doi.org/10.1007/s11306-010-0204-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899017/
https://www.ncbi.nlm.nih.gov/pubmed/20676217
http://dx.doi.org/10.1007/s11306-010-0204-0

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