Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria

Thirteen Hypericum species growing in Bulgaria were investigated for free radical-scavenging activity, antioxidant activity, total tannins and total flavonoids contents. Methanolic extracts from the Hypericum species were analyzed for radical scavenging and antioxidant activities using DPPH-, ABTS-...

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Autores principales: Zheleva-Dimitrova, Dimitrina, Nedialkov, Paraskev, Kitanov, Gerassim
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900065/
https://www.ncbi.nlm.nih.gov/pubmed/20668569
http://dx.doi.org/10.4103/0973-1296.62889
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author Zheleva-Dimitrova, Dimitrina
Nedialkov, Paraskev
Kitanov, Gerassim
author_facet Zheleva-Dimitrova, Dimitrina
Nedialkov, Paraskev
Kitanov, Gerassim
author_sort Zheleva-Dimitrova, Dimitrina
collection PubMed
description Thirteen Hypericum species growing in Bulgaria were investigated for free radical-scavenging activity, antioxidant activity, total tannins and total flavonoids contents. Methanolic extracts from the Hypericum species were analyzed for radical scavenging and antioxidant activities using DPPH-, ABTS- free radicals, total antioxidant activity and inhibition of lipid peroxidation by ferric thiocyanate (FTC) method. Butylated hydroxytoluene and ascorbic acid were used as positive controls. Methanolic extracts from H. cerastoides, H. perforatum and H. maculatum demonstrate the highest antioxidant activities and are potential sources of natural antioxidant compounds. The quantification of tannins and flavanoids were determined in Hypericum species using Folin-Chiocalteu reagent and AlCl3, respectively. The amounts of the tannins ranged from 1.30 ± 0.01 mg/100 g dw in H. elegans to 8.67 ± 0.02 g/100 g dw in H. perforatum. The highest concentration of flavonoids was found in H. cerastoides (1.22 ± 0.02 g/100g dw), and the lowest amount was established in H. olympicum (0.20 ± 0.03 g/100g dw).
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spelling pubmed-29000652010-07-28 Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria Zheleva-Dimitrova, Dimitrina Nedialkov, Paraskev Kitanov, Gerassim Pharmacogn Mag Original Article Thirteen Hypericum species growing in Bulgaria were investigated for free radical-scavenging activity, antioxidant activity, total tannins and total flavonoids contents. Methanolic extracts from the Hypericum species were analyzed for radical scavenging and antioxidant activities using DPPH-, ABTS- free radicals, total antioxidant activity and inhibition of lipid peroxidation by ferric thiocyanate (FTC) method. Butylated hydroxytoluene and ascorbic acid were used as positive controls. Methanolic extracts from H. cerastoides, H. perforatum and H. maculatum demonstrate the highest antioxidant activities and are potential sources of natural antioxidant compounds. The quantification of tannins and flavanoids were determined in Hypericum species using Folin-Chiocalteu reagent and AlCl3, respectively. The amounts of the tannins ranged from 1.30 ± 0.01 mg/100 g dw in H. elegans to 8.67 ± 0.02 g/100 g dw in H. perforatum. The highest concentration of flavonoids was found in H. cerastoides (1.22 ± 0.02 g/100g dw), and the lowest amount was established in H. olympicum (0.20 ± 0.03 g/100g dw). Medknow Publications 2010-04 2010-05-05 /pmc/articles/PMC2900065/ /pubmed/20668569 http://dx.doi.org/10.4103/0973-1296.62889 Text en © Pharmacognosy Magazine http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zheleva-Dimitrova, Dimitrina
Nedialkov, Paraskev
Kitanov, Gerassim
Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
title Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
title_full Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
title_fullStr Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
title_full_unstemmed Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
title_short Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria
title_sort radical scavenging and antioxidant activities of methanolic extracts from hypericum species growing in bulgaria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900065/
https://www.ncbi.nlm.nih.gov/pubmed/20668569
http://dx.doi.org/10.4103/0973-1296.62889
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