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TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation

Transcription of eukaryotic mRNA encoding genes by RNA polymerase II (Pol II) is triggered by the binding of transactivating proteins to enhancer DNA, which stimulates the recruitment of general transcription factors (GTFs; TFIIA, B, D, E, F, H) and Pol II on the cis-linked promoter leading to prein...

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Detalles Bibliográficos
Autores principales: Papai, Gabor, Tripathi, Manish K., Ruhlmann, Christine, Layer, Justin H., Weil, P. Anthony, Schultz, Patrick
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900199/
https://www.ncbi.nlm.nih.gov/pubmed/20559389
http://dx.doi.org/10.1038/nature09080