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Common Polymorphisms in MTNR1B, G6PC2 and GCK Are Associated with Increased Fasting Plasma Glucose and Impaired Beta-Cell Function in Chinese Subjects

BACKGROUND: Previous studies identified melatonin receptor 1B (MTNR1B), islet-specific glucose 6 phosphatase catalytic subunit-related protein (G6PC2), glucokinase (GCK) and glucokinase regulatory protein (GCKR) as candidate genes for type 2 diabetes (T2D) acting through elevated fasting plasma gluc...

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Detalles Bibliográficos
Autores principales: Tam, Claudia Ha Ting, Ho, Janice Sin Ka, Wang, Ying, Lee, Heung Man, Lam, Vincent Kwok Lim, Germer, Soren, Martin, Mitchell, So, Wing Yee, Ma, Ronald Ching Wan, Chan, Juliana Chung Ngor, Ng, Maggie Chor Yin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900202/
https://www.ncbi.nlm.nih.gov/pubmed/20628598
http://dx.doi.org/10.1371/journal.pone.0011428