Successful Amelioration of Mitochondrial Optic Neuropathy Using the Yeast NDI1 Gene in a Rat Animal Model

BACKGROUND: Leber's hereditary optic neuropathy (LHON) is a maternally inherited disorder with point mutations in mitochondrial DNA which result in loss of vision in young adults. The majority of mutations reported to date are within the genes encoding the subunits of the mitochondrial NADH-qui...

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Detalles Bibliográficos
Autores principales: Marella, Mathieu, Seo, Byoung Boo, Thomas, Biju B., Matsuno-Yagi, Akemi, Yagi, Takao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900204/
https://www.ncbi.nlm.nih.gov/pubmed/20628600
http://dx.doi.org/10.1371/journal.pone.0011472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900204/
https://www.ncbi.nlm.nih.gov/pubmed/20628600
http://dx.doi.org/10.1371/journal.pone.0011472

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