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Upregulation of PPARβ/δ Is Associated with Structural and Functional Changes in the Type I Diabetes Rat Diaphragm

BACKGROUND: Diabetes mellitus is associated with alterations in peripheral striated muscles and cardiomyopathy. We examined diaphragmatic function and fiber composition and identified the role of peroxisome proliferator-activated receptors (PPAR α and β/δ) as a factor involved in diaphragm muscle pl...

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Detalles Bibliográficos
Autores principales: Salvi, Nadège, Guellich, Aziz, Michelet, Pierre, Demoule, Alexandre, Le Guen, Morgan, Renou, Laure, Bonne, Gisèle, Riou, Bruno, Langeron, Olivier, Coirault, Catherine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900215/
https://www.ncbi.nlm.nih.gov/pubmed/20628611
http://dx.doi.org/10.1371/journal.pone.0011494