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The Human Gonadotropin Releasing Hormone Type I Receptor Is a Functional Intracellular GPCR Expressed on the Nuclear Membrane
The mammalian type I gonadotropin releasing hormone receptor (GnRH-R) is a structurally unique G protein-coupled receptor (GPCR) that lacks cytoplasmic tail sequences and displays inefficient plasma membrane expression (PME). Compared to its murine counterparts, the primate type I receptor is ineffi...
Autores principales: | Re, Michelle, Pampillo, Macarena, Savard, Martin, Dubuc, Céléna, McArdle, Craig A., Millar, Robert P., Conn, P. Michael, Gobeil, Fernand, Bhattacharya, Moshmi, Babwah, Andy V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900216/ https://www.ncbi.nlm.nih.gov/pubmed/20628612 http://dx.doi.org/10.1371/journal.pone.0011489 |
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