Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain

BACKGROUND: The polycomb group (PcG) protein BMI1 is an important regulator of development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell phenotype and oncogenesis. In particular, its overexpression has been found in several human malignancies including breast cancer....

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Detalles Bibliográficos
Autores principales: Yadav, Ajay K, Sahasrabuddhe, Anagh A, Dimri, Manjari, Bommi, Prashant V, Sainger, Rachana, Dimri, Goberdhan P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900245/
https://www.ncbi.nlm.nih.gov/pubmed/20569464
http://dx.doi.org/10.1186/1476-4598-9-158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900245/
https://www.ncbi.nlm.nih.gov/pubmed/20569464
http://dx.doi.org/10.1186/1476-4598-9-158

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