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Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain
BACKGROUND: The polycomb group (PcG) protein BMI1 is an important regulator of development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell phenotype and oncogenesis. In particular, its overexpression has been found in several human malignancies including breast cancer....
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900245/ https://www.ncbi.nlm.nih.gov/pubmed/20569464 http://dx.doi.org/10.1186/1476-4598-9-158 |