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Predicting nucleosome positioning using a duration Hidden Markov Model

BACKGROUND: The nucleosome is the fundamental packing unit of DNAs in eukaryotic cells. Its detailed positioning on the genome is closely related to chromosome functions. Increasing evidence has shown that genomic DNA sequence itself is highly predictive of nucleosome positioning genome-wide. Theref...

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Detalles Bibliográficos
Autores principales: Xi, Liqun, Fondufe-Mittendorf, Yvonne, Xia, Lei, Flatow, Jared, Widom, Jonathan, Wang, Ji-Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900280/
https://www.ncbi.nlm.nih.gov/pubmed/20576140
http://dx.doi.org/10.1186/1471-2105-11-346