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Computational Analysis of Whole-Genome Differential Allelic Expression Data in Human

Allelic imbalance (AI) is a phenomenon where the two alleles of a given gene are expressed at different levels in a given cell, either because of epigenetic inactivation of one of the two alleles, or because of genetic variation in regulatory regions. Recently, Bing et al. have described the use of...

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Detalles Bibliográficos
Autores principales: Wagner, James R., Ge, Bing, Pokholok, Dmitry, Gunderson, Kevin L., Pastinen, Tomi, Blanchette, Mathieu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900287/
https://www.ncbi.nlm.nih.gov/pubmed/20628616
http://dx.doi.org/10.1371/journal.pcbi.1000849