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Redundancy and the Evolution of Cis-Regulatory Element Multiplicity

The promoter regions of many genes contain multiple binding sites for the same transcription factor (TF). One possibility is that this multiplicity evolved through transitional forms showing redundant cis-regulation. To evaluate this hypothesis, we must disentangle the relative contributions of diff...

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Detalles Bibliográficos
Autores principales: Paixão, Tiago, Azevedo, Ricardo B. R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900288/
https://www.ncbi.nlm.nih.gov/pubmed/20628617
http://dx.doi.org/10.1371/journal.pcbi.1000848