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Large-Scale Analysis of Network Bistability for Human Cancers
Protein–protein interaction and gene regulatory networks are likely to be locked in a state corresponding to a disease by the behavior of one or more bistable circuits exhibiting switch-like behavior. Sets of genes could be over-expressed or repressed when anomalies due to disease appear, and the ci...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900289/ https://www.ncbi.nlm.nih.gov/pubmed/20628618 http://dx.doi.org/10.1371/journal.pcbi.1000851 |