Predicting Important Residues and Interaction Pathways in Proteins Using Gaussian Network Model: Binding and Stability of HLA Proteins

A statistical thermodynamics approach is proposed to determine structurally and functionally important residues in native proteins that are involved in energy exchange with a ligand and other residues along an interaction pathway. The structure-function relationships, ligand binding and allosteric a...

Descripción completa

Detalles Bibliográficos
Autores principales: Haliloglu, Turkan, Gul, Ahmet, Erman, Burak
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900293/
https://www.ncbi.nlm.nih.gov/pubmed/20628622
http://dx.doi.org/10.1371/journal.pcbi.1000845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900293/
https://www.ncbi.nlm.nih.gov/pubmed/20628622
http://dx.doi.org/10.1371/journal.pcbi.1000845

Ejemplares similares