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TOPO3α Influences Antigenic Variation by Monitoring Expression-Site-Associated VSG Switching in Trypanosoma brucei

Homologous recombination (HR) mediates one of the major mechanisms of trypanosome antigenic variation by placing a different variant surface glycoprotein (VSG) gene under the control of the active expression site (ES). It is believed that the majority of VSG switching events occur by duplicative gen...

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Detalles Bibliográficos
Autores principales: Kim, Hee-Sook, Cross, George A. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900300/
https://www.ncbi.nlm.nih.gov/pubmed/20628569
http://dx.doi.org/10.1371/journal.ppat.1000992