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Functional Genetic Diversity among Mycobacterium tuberculosis Complex Clinical Isolates: Delineation of Conserved Core and Lineage-Specific Transcriptomes during Intracellular Survival

Tuberculosis exerts a tremendous burden on global health, with ∼9 million new infections and ∼2 million deaths annually. The Mycobacterium tuberculosis complex (MTC) was initially regarded as a highly homogeneous population; however, recent data suggest the causative agents of tuberculosis are more...

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Detalles Bibliográficos
Autores principales: Homolka, Susanne, Niemann, Stefan, Russell, David G., Rohde, Kyle H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900310/
https://www.ncbi.nlm.nih.gov/pubmed/20628579
http://dx.doi.org/10.1371/journal.ppat.1000988