A B56γ mutation in lung cancer disrupts the p53-dependent tumor suppressor function of protein phosphatase 2A

Earlier studies have demonstrated both p53-dependent and -independent tumor suppressive functions of B56γ-specific protein phosphatase 2A (B56γ-PP2A). In the absence of p53, B56γ-PP2A can inhibit cell proliferation and cell transformation by an unknown mechanism. In the presence of p53, upon DNA dam...

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Detalles Bibliográficos
Autores principales: Shouse, Geoffrey P., Nobumori, Yumiko, Liu, Xuan
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900437/
https://www.ncbi.nlm.nih.gov/pubmed/20473327
http://dx.doi.org/10.1038/onc.2010.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900437/
https://www.ncbi.nlm.nih.gov/pubmed/20473327
http://dx.doi.org/10.1038/onc.2010.161

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