Cargando…
A B56γ mutation in lung cancer disrupts the p53-dependent tumor suppressor function of protein phosphatase 2A
Earlier studies have demonstrated both p53-dependent and -independent tumor suppressive functions of B56γ-specific protein phosphatase 2A (B56γ-PP2A). In the absence of p53, B56γ-PP2A can inhibit cell proliferation and cell transformation by an unknown mechanism. In the presence of p53, upon DNA dam...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900437/ https://www.ncbi.nlm.nih.gov/pubmed/20473327 http://dx.doi.org/10.1038/onc.2010.161 |