Assessment of immunogenicity of romiplostim in clinical studies with ITP subjects

Romiplostim is an Fc-peptide fusion protein that activates intracellular transcriptional pathways via the thrombopoietin (TPO) receptor leading to increased platelet production. Romiplostim has been engineered to have no amino acid sequence homology to endogenous TPO. Recombinant protein therapeutic...

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Detalles Bibliográficos
Autores principales: Jawa, Vibha, Hokom, Martha, Hu, Zheng, El-Abaadi, Naglaa, Zhuang, Yao, Berger, Dietmar, Gupta, Shalini, Swanson, Steven J., Chirmule, Narendra
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900600/
https://www.ncbi.nlm.nih.gov/pubmed/20155267
http://dx.doi.org/10.1007/s00277-010-0908-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900600/
https://www.ncbi.nlm.nih.gov/pubmed/20155267
http://dx.doi.org/10.1007/s00277-010-0908-2

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