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A novel and efficient method to prepare 2-aryltetrahydrofuran-2-ylphosphonic acids

A novel one-pot method was developed for the synthesis of the title compounds starting from 4-chloro-1-aryl-1-butanones 1, phosphorus trichloride and acetic acid. The end products 2 were obtained in 20–94% yield. The cyclization step under acidic conditions probably occurs as a result of anchimeric...

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Detalles Bibliográficos
Autores principales: Komissarov, Vsevolod V, Kritzyn, Anatoly M, Vepsäläinen, Jouko J
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900910/
https://www.ncbi.nlm.nih.gov/pubmed/20625523
http://dx.doi.org/10.3762/bjoc.6.63