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A novel and efficient method to prepare 2-aryltetrahydrofuran-2-ylphosphonic acids
A novel one-pot method was developed for the synthesis of the title compounds starting from 4-chloro-1-aryl-1-butanones 1, phosphorus trichloride and acetic acid. The end products 2 were obtained in 20–94% yield. The cyclization step under acidic conditions probably occurs as a result of anchimeric...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900910/ https://www.ncbi.nlm.nih.gov/pubmed/20625523 http://dx.doi.org/10.3762/bjoc.6.63 |