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Identification of an immediate Foxp3(−) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice
CD4(+)CD25(+) regulatory T cells (T reg cells) expressing the transcription factor Foxp3 can be induced from peripheral T cell receptor (TCR) transgenic CD4(+)CD25(−)Foxp3(−) T cells stimulated with noninflammatory dendritic cells presenting low amounts of agonist cognate antigen. However, limited e...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901063/ https://www.ncbi.nlm.nih.gov/pubmed/20584884 http://dx.doi.org/10.1084/jem.20100045 |