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Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis

The ability of the adaptive immune system to restrict Mycobacterium tuberculosis (Mtb) is impeded by activated Foxp3(+) regulatory T (T reg) cells. The importance of pathogen-specific T reg cells in this process has not been addressed. We show that T reg cell expansion after aerosol Mtb infection do...

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Detalles Bibliográficos
Autores principales: Shafiani, Shahin, Tucker-Heard, Glady’s, Kariyone, Ai, Takatsu, Kiyoshi, Urdahl, Kevin B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901066/
https://www.ncbi.nlm.nih.gov/pubmed/20547826
http://dx.doi.org/10.1084/jem.20091885