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Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis
The ability of the adaptive immune system to restrict Mycobacterium tuberculosis (Mtb) is impeded by activated Foxp3(+) regulatory T (T reg) cells. The importance of pathogen-specific T reg cells in this process has not been addressed. We show that T reg cell expansion after aerosol Mtb infection do...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901066/ https://www.ncbi.nlm.nih.gov/pubmed/20547826 http://dx.doi.org/10.1084/jem.20091885 |