The Plasmodium eukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

Sporozoites, the invasive form of malaria parasites transmitted by mosquitoes, are quiescent while in the insect salivary glands. Sporozoites only differentiate inside of the hepatocytes of the mammalian host. We show that sporozoite latency is an active process controlled by a eukaryotic initiation...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Fennell, Clare, Ranford-Cartwright, Lisa, Sakthivel, Ramanavelan, Gueirard, Pascale, Meister, Stephan, Caspi, Anat, Doerig, Christian, Nussenzweig, Ruth S., Tuteja, Renu, Sullivan, William J., Roos, David S., Fontoura, Beatriz M.A., Ménard, Robert, Winzeler, Elizabeth A., Nussenzweig, Victor
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901070/
https://www.ncbi.nlm.nih.gov/pubmed/20584882
http://dx.doi.org/10.1084/jem.20091975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901070/
https://www.ncbi.nlm.nih.gov/pubmed/20584882
http://dx.doi.org/10.1084/jem.20091975

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