IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform

The quality of a Th1 response can be a prospective correlate of vaccine-mediated protection against certain intracellular pathogens. Using two distinct vaccine platforms, we evaluate the influence of interleukin (IL) 10 production on the magnitude, quality, and protective capacity of CD4(+) T cell r...

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Detalles Bibliográficos
Autores principales: Darrah, Patricia A., Hegde, Sonia T., Patel, Dipti T., Lindsay, Ross W. B., Chen, Linda, Roederer, Mario, Seder, Robert A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901071/
https://www.ncbi.nlm.nih.gov/pubmed/20530206
http://dx.doi.org/10.1084/jem.20092532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901071/
https://www.ncbi.nlm.nih.gov/pubmed/20530206
http://dx.doi.org/10.1084/jem.20092532

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