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IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform
The quality of a Th1 response can be a prospective correlate of vaccine-mediated protection against certain intracellular pathogens. Using two distinct vaccine platforms, we evaluate the influence of interleukin (IL) 10 production on the magnitude, quality, and protective capacity of CD4(+) T cell r...
Autores principales: | Darrah, Patricia A., Hegde, Sonia T., Patel, Dipti T., Lindsay, Ross W. B., Chen, Linda, Roederer, Mario, Seder, Robert A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901071/ https://www.ncbi.nlm.nih.gov/pubmed/20530206 http://dx.doi.org/10.1084/jem.20092532 |
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