ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification

Ataxia telangiectasia mutated (ATM) deficiency predisposes humans and mice to T lineage lymphomas with recurrent chromosome 14 translocations involving the T cell receptor α/δ (Tcra/d) locus. Such translocations have been thought to result from aberrant repair of DNA double-strand breaks (DSBs) duri...

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Detalles Bibliográficos
Autores principales: Zha, Shan, Bassing, Craig H., Sanda, Takaomi, Brush, James W., Patel, Harin, Goff, Peter H., Murphy, Michael M., Tepsuporn, Suprawee, Gatti, Richard A., Look, A. Thomas, Alt, Frederick W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901073/
https://www.ncbi.nlm.nih.gov/pubmed/20566716
http://dx.doi.org/10.1084/jem.20100285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901073/
https://www.ncbi.nlm.nih.gov/pubmed/20566716
http://dx.doi.org/10.1084/jem.20100285

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