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ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification

Ataxia telangiectasia mutated (ATM) deficiency predisposes humans and mice to T lineage lymphomas with recurrent chromosome 14 translocations involving the T cell receptor α/δ (Tcra/d) locus. Such translocations have been thought to result from aberrant repair of DNA double-strand breaks (DSBs) duri...

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Detalles Bibliográficos
Autores principales:	Zha, Shan, Bassing, Craig H., Sanda, Takaomi, Brush, James W., Patel, Harin, Goff, Peter H., Murphy, Michael M., Tepsuporn, Suprawee, Gatti, Richard A., Look, A. Thomas, Alt, Frederick W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901073/ https://www.ncbi.nlm.nih.gov/pubmed/20566716 http://dx.doi.org/10.1084/jem.20100285

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