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Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver

BACKGROUND: The unbound, free concentration (B(f)) of unconjugated bilirubin (UCB), and not the total UCB level, has been shown to correlate with bilirubin cytotoxicity, but the key molecular mechanisms accounting for the toxic effects of UCB are largely unknown. FINDINGS: Mouse liver mitochondria i...

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Detalles Bibliográficos
Autores principales: Malik, Safarina G, Irwanto, K Astrid, Ostrow, J Donald, Tiribelli, Claudio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901210/
https://www.ncbi.nlm.nih.gov/pubmed/20534120
http://dx.doi.org/10.1186/1756-0500-3-162