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Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver
BACKGROUND: The unbound, free concentration (B(f)) of unconjugated bilirubin (UCB), and not the total UCB level, has been shown to correlate with bilirubin cytotoxicity, but the key molecular mechanisms accounting for the toxic effects of UCB are largely unknown. FINDINGS: Mouse liver mitochondria i...
Autores principales: | Malik, Safarina G, Irwanto, K Astrid, Ostrow, J Donald, Tiribelli, Claudio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901210/ https://www.ncbi.nlm.nih.gov/pubmed/20534120 http://dx.doi.org/10.1186/1756-0500-3-162 |
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