Worldwide Distribution of the MYH9 Kidney Disease Susceptibility Alleles and Haplotypes: Evidence of Historical Selection in Africa

MYH9 was recently identified as renal susceptibility gene (OR 3–8, p<10(−8)) for major forms of kidney disease disproportionately affecting individuals of African descent. The risk haplotype (E-1) occurs at much higher frequencies in African Americans (≥60%) than in European Americans (<4%), r...

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Detalles Bibliográficos
Autores principales: Oleksyk, Taras K., Nelson, George W., An, Ping, Kopp, Jeffrey B., Winkler, Cheryl A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901326/
https://www.ncbi.nlm.nih.gov/pubmed/20634883
http://dx.doi.org/10.1371/journal.pone.0011474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901326/
https://www.ncbi.nlm.nih.gov/pubmed/20634883
http://dx.doi.org/10.1371/journal.pone.0011474

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