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Polycomb Target Genes Are Silenced in Multiple Myeloma

Multiple myeloma (MM) is a genetically heterogeneous disease, which to date remains fatal. Finding a common mechanism for initiation and progression of MM continues to be challenging. By means of integrative genomics, we identified an underexpressed gene signature in MM patient cells compared to nor...

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Detalles Bibliográficos
Autores principales: Kalushkova, Antonia, Fryknäs, Mårten, Lemaire, Miguel, Fristedt, Charlotte, Agarwal, Prasoon, Eriksson, Maria, Deleu, Sarah, Atadja, Peter, Österborg, Anders, Nilsson, Kenneth, Vanderkerken, Karin, Öberg, Fredrik, Jernberg-Wiklund, Helena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901331/
https://www.ncbi.nlm.nih.gov/pubmed/20634887
http://dx.doi.org/10.1371/journal.pone.0011483