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CRTH2 expression on T cells in asthma

Mast cell-derived prostaglandin D(2) (PGD(2)) is the major prostanoid found within the airway of asthmatics immediately following allergen challenge. PGD(2) has been shown to have chemokinetic effects on eosinophils and T helper type 2 (Th2) cells in vitro. This occurs through the interaction of PGD...

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Detalles Bibliográficos
Autores principales: Mutalithas, K, Guillen, C, Day, C, Brightling, C E, Pavord, I D, Wardlaw, A J
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901512/
https://www.ncbi.nlm.nih.gov/pubmed/20491797
http://dx.doi.org/10.1111/j.1365-2249.2010.04161.x