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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
The immunity-related GTPases (IRGs) constitute an interferon-induced intracellular resistance mechanism in mice against Toxoplasma gondii. IRG proteins accumulate on the parasitophorous vacuole membrane (PVM), leading to its disruption and to death of the parasite. How IRGs target the PVM is unknown...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901525/ https://www.ncbi.nlm.nih.gov/pubmed/20109161 http://dx.doi.org/10.1111/j.1462-5822.2010.01443.x |