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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

The immunity-related GTPases (IRGs) constitute an interferon-induced intracellular resistance mechanism in mice against Toxoplasma gondii. IRG proteins accumulate on the parasitophorous vacuole membrane (PVM), leading to its disruption and to death of the parasite. How IRGs target the PVM is unknown...

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Detalles Bibliográficos
Autores principales:	Khaminets, Aliaksandr, Hunn, Julia P, Könen-Waisman, Stephanie, Zhao, Yang O, Preukschat, Daniela, Coers, Jörn, Boyle, Jon P, Ong, Yi-Ching, Boothroyd, John C, Reichmann, Gabriela, Howard, Jonathan C
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2010
Materias:	Original articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901525/ https://www.ncbi.nlm.nih.gov/pubmed/20109161 http://dx.doi.org/10.1111/j.1462-5822.2010.01443.x

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