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Insights into Protein Sequence and Structure-Derived Features Mediating 3D Domain Swapping Mechanism using Support Vector Machine Based Approach

3-dimensional domain swapping is a mechanism where two or more protein molecules form higher order oligomers by exchanging identical or similar subunits. Recently, this phenomenon has received much attention in the context of prions and neurodegenerative diseases, due to its role in the functional r...

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Detalles Bibliográficos
Autores principales: Shameer, Khader, Pugalenthi, Ganesan, Kandaswamy, Krishna Kumar, Suganthan, Ponnuthurai N., Archunan, Govindaraju, Sowdhamini, Ramanathan
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901629/
https://www.ncbi.nlm.nih.gov/pubmed/20634983