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Insights into Protein Sequence and Structure-Derived Features Mediating 3D Domain Swapping Mechanism using Support Vector Machine Based Approach
3-dimensional domain swapping is a mechanism where two or more protein molecules form higher order oligomers by exchanging identical or similar subunits. Recently, this phenomenon has received much attention in the context of prions and neurodegenerative diseases, due to its role in the functional r...
Autores principales: | Shameer, Khader, Pugalenthi, Ganesan, Kandaswamy, Krishna Kumar, Suganthan, Ponnuthurai N., Archunan, Govindaraju, Sowdhamini, Ramanathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901629/ https://www.ncbi.nlm.nih.gov/pubmed/20634983 |
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