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Increased Plasma Levels of 8-Hydroxydeoxyguanosine Are Associated with Development of Colorectal Tumors

Increased oxidative stress is generally thought to be associated with tumorigenesis. In this cross-sectional study, we evaluated plasma 8-hydroxydeoxyguanosine (8-OHdG) levels in patients with colorectal adenoma and cancer, as a surrogate marker of oxidative damage to deoxyribonucleic acid (DNA). We...

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Detalles Bibliográficos
Autores principales: Sato, Takeshi, Takeda, Hiroaki, Otake, Sayaka, Yokozawa, Junji, Nishise, Shoichi, Fujishima, Shoichiro, Orii, Tomohiko, Fukui, Tadahisa, Takano, Jun, Sasaki, Yu, Nagino, Ko, Iwano, Daisuke, Yaoita, Takao, Kawata, Sumio
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901765/
https://www.ncbi.nlm.nih.gov/pubmed/20664732
http://dx.doi.org/10.3164/jcbn.10-12