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Tbx3 improves the germ-line competency of induced pluripotent stem cells
Induced pluripotent stem (iPS) cells can be obtained through the introduction of defined factors into somatic cells1. The combination of Oct4, Sox2 and Klf4 (OSK) constitutes the minimal requirement for generating iPS cells from mouse embryonic fibroblasts (MEFs). These cells are thought to resemble...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901797/ https://www.ncbi.nlm.nih.gov/pubmed/20139965 http://dx.doi.org/10.1038/nature08735 |