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Tbx3 improves the germ-line competency of induced pluripotent stem cells

Induced pluripotent stem (iPS) cells can be obtained through the introduction of defined factors into somatic cells1. The combination of Oct4, Sox2 and Klf4 (OSK) constitutes the minimal requirement for generating iPS cells from mouse embryonic fibroblasts (MEFs). These cells are thought to resemble...

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Detalles Bibliográficos
Autores principales: Han, Jianyong, Yuan, Ping, Yang, Henry, Zhang, Jinqiu, Soh, Boon Seng, Li, Pin, Lim, Siew Lan, Cao, Suying, Tay, Junliang, Orlov, Yuriy L., Lufkin, Thomas, Ng, Huck-Hui, Tam, Wai-Leong, Lim, Bing
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901797/
https://www.ncbi.nlm.nih.gov/pubmed/20139965
http://dx.doi.org/10.1038/nature08735