Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

Mechanical forces are central to developmental, physiological and pathological processes1. However, limited understanding of force transmission within sub-cellular structures is a major obstacle to unravelling molecular mechanisms. Here we describe the development of a calibrated biosensor that meas...

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Detalles Bibliográficos
Autores principales: Grashoff, Carsten, Hoffman, Brenton D., Brenner, Michael D., Zhou, Ruobo, Parsons, Maddy, Yang, Michael T., McLean, Mark A., Sligar, Stephen G., Chen, Christopher S., Ha, Taekjip, Schwartz, Martin A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901888/
https://www.ncbi.nlm.nih.gov/pubmed/20613844
http://dx.doi.org/10.1038/nature09198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901888/
https://www.ncbi.nlm.nih.gov/pubmed/20613844
http://dx.doi.org/10.1038/nature09198

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