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Network organization of the human autophagy system

Autophagy, the process by which proteins and organelles are sequestered in autophagosomal vesicles and delivered to the lysosome/vacuole for degradation, provides a primary route for turnover of stable and defective cellular proteins. Defects in this system are linked with numerous human diseases. W...

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Detalles Bibliográficos
Autores principales: Behrends, Christian, Sowa, Mathew E., Gygi, Steven P., Harper, J. Wade
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901998/
https://www.ncbi.nlm.nih.gov/pubmed/20562859
http://dx.doi.org/10.1038/nature09204