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Superficial Dsg2 Expression Limits Epidermal Blister Formation Mediated by Pemphigus Foliaceus Antibodies and Exfoliative Toxins

Cell-cell adhesion mediated by desmosomes is crucial for maintaining proper epidermal structure and function, as evidenced by several severe and potentially fatal skin disorders involving impairment of desmosomal proteins. Pemphigus foliaceus (PF) and staphylococcal scalded skin syndrome (SSSS) are...

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Detalles Bibliográficos
Autores principales: Brennan, Donna, Hu, Ying, Medhat, Walid, Dowling, Alicia, Mahoney, Mỹ G.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902105/
https://www.ncbi.nlm.nih.gov/pubmed/20631906
http://dx.doi.org/10.1155/2010/410278