Cargando…

Do Alterations in Mitochondrial DNA Play a Role in Breast Carcinogenesis?

A considerable body of evidence supports a role for oxidative stress in breast carcinogenesis. Due to their role in producing energy via oxidative phosphorylation, the mitochondria are a major source of production of reactive oxygen species, which may damage DNA. The mitochondrial genome may be part...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohan, Thomas E., Wong, Lee-Jun, Wang, Tao, Haines, Jonathan, Kabat, Geoffrey C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902128/
https://www.ncbi.nlm.nih.gov/pubmed/20628528
http://dx.doi.org/10.1155/2010/604304